Buy Belbien (zolpidem) Online

Belbien-Zolpidem

Belbien is the brand name for Zolpidem. Zolpidem is a non-benzodiazepine sedative-hypnotic for the short-term treatment of insomnia .Although chemically unrelated to other hypnotics such as the benzodiazepines or barbiturates; Zolpidem does share some pharmacological actions with these drugs. Unlike the benzodiazepines, Zolpidem produces muscle relaxation and anticonvulsant effects only at doses much higher than the hypnotic dose. Zolpidem has a short half-life and no active metabolites. Therefore, a next-day ‘‘hangover’’ effect and CNS depression are less for Zolpidem that the barbiturates. It acts on the CNS and produces sedation, sleep, and inhibition of anxiety. It is also used for involuntary muscle spasms and seizures. It is also sometimes used for restless legs syndrome.

Common side effects are drowsiness ,tiredness, headache, dizziness ,lightheadedness ,’drugged feeling, unsteady walking, difficulty keeping balance,nausea,constipation,diarrhea,gas,heartburn ,stomach pain or tenderness,changes in appetite agitation, sleepiness, and lack of coordination. Prolonged use of this can cause tolerance, dependence, and withdrawal effects if stopped abruptly. It should not be used in pregnancy and lactation as it can cause harmful side effects or taken with caution.

History

Zolpidem was first used in Europe in 1988, and Synthelabo was the company that brought it to market. Synthelabo and Searle worked together to bring it to market in the United States, and it was approved in 1992 under the brand name “Ambien.” In 2007, it was made available as a generic medicine.

The American Geriatrics Society stated in 2015 that zolpidem, eszopiclone, and zaleplon matched the Beers criteria and should be avoided in people aged 65 and up “because of their link to hazards compared with their poor efficacy in treating insomnia.’’

 The strength of the advice that older persons avoid zolpidem is “strong,” according to the AGS, and the quality of the evidence is “high.”

However, with time it came to attention that due to its high efficacy, it can be abused. The study named “misuse of zolpidem” favors the potential of abuse and dependence of zolpidem and emphasizes reinforcement of monitoring for this medication. This medication is categorized as SCHEDULE IV by the Drug Enforcement Authority (DEA), which means it is a controlled substance but is comparatively less addictive. This data needs to be transferred to health professionals.

Before you go ahead and buy Belbien online there are many factors one needs consider before making such a decision. This study has been designed to help you make an informed decision.

Uses of Belbien

Belbien is primarily for sleep disorders. It is used for short term but not for long term as it can disturb REM sleep.

Sleep Disorder

Zolpidem mainly produces hypnotic effect-decreases sleep latency and increases duration of sleep time in insomnia. It produces near-normal sleep like benzodiazepines with minimal alteration in REM sleep; causes minimal hangover effects and rebound insomnia; less likely to produce tolerance and drug dependence; lacks anticonvulsant, anti-anxiety and muscle relaxant effects.

Anti-anxiety:

Belbien (Zolpidem) is used for anxiety-related insomnia but its use as an anti-anxiety treatment is not proven.

How to take Belbien

Oral (Tablets and liquid form)

Intravenous (IV)

Intramuscular (IM)

Sublingual

The recommended adult dose of belbien is 10 mg as conventional tablets or spray or 12.5 mg as extended-release tablets.

Belbien v/s Valium:

Belbien is zolpidem and Valium is diazepam. Both belongs to different groups. Belbien is no benzodiazepine hypnotic and diazepam is a benzodiazepine.

Belbien is used for the treatment of insomnia but valium has multiple uses in addition to sleep disorders. According to a research, efficacy of belbien is much more than valium for insomnia treat.

Belbien produces near-normal sleep like valium with minimal alteration in REM sleep; causes minimal hangover effects and rebound insomnia; less likely to produce tolerance and drug dependence; lacks anticonvulsant, anti-anxiety and muscle relaxant effects.

Belbien v/s Limovan:

Belbien is zolpidem and Limovan is zopiclone. Both are used for the short term treatment of insomnia. Belbien decreases sleep latency and increases duration of sleep time in insomnia but in high doses, inhibits the REM sleep. Limovan produces near normal sleep like benzodiazepines hence are more addictive.

Lunesta is longer acting. It may be more effective in helping you stay asleep than the immediate-release form of belbien.

According to a double blind comparative study of zolipdem and zopiclone , Belbien showed significantly less rebound on discontinuation and was better tolerated.

Belbien v/Zaleplon:

It is similar to the Zolpidem and selectively stimulates BZ1 receptors. Zaleplon causes rapid onset of sleep and belbien causes inhibition of REM sleep .Amnesia and impairment of psychomotor activity is less as compared to benzodiazepines. Dependence and tolerance has not been reported with zaleplon.

Belbien vs melatonin :

Both are used for insomnia. According to a comparative study, both melatonin and belbien were well tolerated with dizziness and headache as the only reported adverse effect. Melatonin demonstrated no significant difference in effective disturbance and adverse effects as compared to Zolpidem. Melatonin cause no dependence as compared to Zolpidem.

These are due to the extension of its pharmacological actions. It affects different systems:                              

Sedation and amnesia:

Belbien is a sedative hypnotic reduces CNS functions, including memory. Anterograde amnesia is dose dependent. Following can occur:

  • Asthenia (a chronic medical condition in which person is unable to move certain body parts)
  • Fatigue
  • Ataxia (a movement disorder in which there is lack of inability to coordinate)
  • Impairment of concentration
  • Somnolence

Cognitive Functions:

The benzodiazepines and benzodiazepine-like agents affect mental efficiency, e.g., concentration, attention and vigilance. The risk of confusion is greater in the elderly and in patients with cerebral impairment.

Anxiety, restlessness:

An increase in daytime anxiety and/or restlessness has been observed during treatment with Belbien. This may be a manifestation of interpose withdrawal, due to the short elimination half-life of the drug.

Complex sleep behaviors:

Complex sleep behaviors have been recorded in some patients taking BELBIEN. Complex sleep behavior includes:

  • sleep-walking,
  • sleep-driving
  • Engaging in other activities while not fully awake.
  • preparing and eating food, making phone calls, or having sex

These practices may happen following the first or any subsequent utilization of Belbien. Patients can be truly harmed or harm others during complex sleep behaviors. Such harms might be deadly. Patients normally don’t recollect these occasions. Post marketing reports have shown that complex sleep behaviors may happen with Belbien at suggested dosages, with or without the accompanying utilization of liquor or other focal sensory systems (CNS) depressants (see DRUG INTERACTIONS). Stop taking Belbien quickly if a patient encounters any such behaviors.

Drug dependence and withdrawal::

When used for prolonged period of time, Belbien can cause dependence. In such cases, withdrawal effects can occur when drug is suddenly stopped. Withdrawal symptoms, similar in character to those noted with barbiturates and alcohol, include:

  • convulsions
  • tremor
  • abdominal and
  • muscle cramp
  • vomiting
  • sweating
  • dysphoria
  • perceptual disturbances
  • insomnia
  • Rebound insomnia (A transient syndrome, whereby the symptoms that led to treatment with a sedative/hypnotic agent may recur in an enhanced form, upon treatment withdrawal. It may be accompanied by other reactions, including mood changes, anxiety and restlessness.)

Tolerance:

Tolerance can occur with chronic use of Belbien tolerance is the decrease in the responsiveness, occurs when drugs are used chronically. Thus to maintain the pharmacological action of the drug, dose of the drug have to be increased with the passage of time.

Long term use of benzodiazepines for insomnia is not recommended

Gastrointestinal effects:

Following gastrointestinal effects can occur:

  • Nausea and vomiting
  • Abdominal pain
  • Increase salivation that can cause respiratory difficulty.
  • Diarrhea
  • Dyspepsia; hepatitis

Kidney/genitourinary:

Rarely, acute interstitial nephritis can occur.

Respiratory:

  • Increase in viral infections.
  • Dyspnea

Dermatologic effects:

  • Rash
  • Urticaria
  • Spots on skin
  • Sweating
  • Pruritus
  • Angioedema. Angioedema that occur can involve tongue, glottis or larynx which lead to airway obstruction that can be fatal if not managed.
  • Anaphylactic reactions have been reported very rarely.

Can I take Belbien (Zolpidem) if I am pregnant or breastfeeding?

No, Belbien (Zolpidem) is harmful to the baby both during pregnancy and breastfeeding. Zolpidem is classified in FDA pregnancy category C, which means there is a possible risk to the fetus and it should be used only when benefits outweighs risks. It has the potential to cross the placental barrier in pregnancy. For lactation, it is categorized as L3, which means a breastfeeding child can be at risk. So it should be avoided. It is excreted in very low amount in human milk i.e 0.02%.

It can cause lethal effects in the newborn such as respiratory depression which can lead to mortality of the newborn. It can also cause hypotonia known as Floppy baby syndrome, in which the baby doesn’t have any tone and feel limp, like a rag doll. It can also cause other symptoms of CNS depression and withdrawal effects even in the newborn. It can lead to congenital malformations such as cleft palate.

How quickly does the treatment work?

Belbien generally has an intermediate onset of action. When administered, it acts within half an hour.

Is it safe to take Belbien?

No, due to concerns related to dependency and tolerance, Zolpidem should be used for short term.

How long does a dose of Belbien last?

Belbien has the half-life of 2.6 hours. Full elimination of belbien takes 11 to 16 hours.

Are there any side effects of the treatment?

Yes, therapeutic doses of Belbien have side effects but these are less likely to be lethal.

Do I require a prescription for taking Belbien?

Yes, you should have the prescription for taking Belbien because it is only available on prescription by a certified doctor only. This is due to its fatal effects if misused. Having diazepam without a prescription is illegal.

Why is it not safe to buy Belbien online?

It is not safe because this drug may be fake. FDA strongly discourages consumers from buying online because of the issue of counterfeit. Counterfeited drug can be lethal if used.

I cannot swallow tablets, what should I take?

You can take Oral Zolpidem spray. It comes in 3 forms.

Is this treatment a safe option for children?

No, it is not recommended for use in peadiatric age group.

How long do I have to take Belbien (Zolpidem)?

It should be used for short term. Treatment with Belbien should usually not exceed 7-10 consecutive days. Use for more than 2-3 consecutive weeks requires complete re-evaluation of the patient. Prescriptions for Belbien should be written for short-term use (7-10 days) and it should not be prescribed in quantities exceeding a 1-month supply. You need to adhere to the directions of your primary care physician cautiously. Long term treatment can cause inhibition of REM sleep.

Can I take Belbien (Zolpidem) with other medication?

Certain drugs shouldn’t be used alongside Belbien because some drugs decrease their efficacy and the interaction of some drugs with it can cause lethal effects. If you are taking other medicines you must tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food store. Some medicines may interfere with the absorption of Iimovane. These include:

  • medicines to treat depression, anxiety and mental illness
  • St John’s wort, (hypericum), a herbal remedy for depression
  • other medications which may cause drowsiness
  • benzodiazepines (medicines used as sedatives or to treat anxiety)
  • pain relievers, such as opioids or narcotic analgesics
  • alcohol, (ethanol), contained in some medicines eg cough syrups
  • muscle relaxants
  • antihistamines
  • medicines used to treat epilepsy
  • antiviral medication
  • rifampicin, erythromycin or clarithromycin (medicines used to treat infections)
  • ketoconazole or itraconazole (medicines used to treat fungal infections)

These medicines may be affected by Belbien or may affect how well it works. You may need to take different amounts of your medicine or different medicines. Your doctor or pharmacist will advise you. Your doctor or pharmacist has more information on medicines to be careful with or to avoid while taking Belbien.

Can I use Belbien with alcohol?

No. Combining Belbien with alcohol is dangerous and can cause respiratory depression (slowed breathing, not getting enough oxygen), extreme sedation, coma, or even death.

Is Belbien a muscle relaxant?

Belbien is not indicated for use as a muscle relaxant. Valium is used for muscle relaxation due to its effect on neurons in the spinal cord. Occasionally, Belbien may be used off-label for muscle spasms, but it is not a first-line or common treatment for muscle spasms.